LOCAL Ketamine Infusion Clinic in Indianapolis
Accentus Mental Health
Any decision as to whether to prescribe or administer ketamine will be solely determined in the professional clinical judgment of the licensed practitioner.
Treatment-resistant depression is a complex and challenging condition that affects individuals and families across the Indianapolis community. When traditional treatments like antidepressants have not provided relief, innovative options like IV ketamine therapy may offer new hope and faster symptom relief. At Accentus Mental Health, we provide medically supervised ketamine infusions in a safe, supportive setting.
What is Ketamine Infusion Therapy?
Originally developed as an anesthetic and widely used during the Vietnam War, ketamine has since emerged as a treatment for mental health conditions. In clinical settings, it is delivered intravenously. It works differently from antidepressants by targeting brain pathways linked to mood and emotional regulation.
Ketamine is known for its rapid ability to reduce depressive symptoms, particularly for individuals who have not found relief with traditional treatments. Understanding how IV ketamine works can help you explore whether this treatment may be right for you.
How IV Ketamine Therapy Works
IV ketamine therapy works by influencing glutamate, a key neurotransmitter involved in mood regulation and brain function. This process helps promote new neural connections and restores communication between brain pathways affected by depression.
Unlike traditional antidepressants, which may take weeks, ketamine can produce relief more quickly.
Is Ketamine Therapy Right for You?
Ketamine therapy may be an option for individuals experiencing treatment-resistant depression or those who have not found relief from other mental health conditions via traditional medications. At Accentus Mental Health, each patient undergoes a comprehensive evaluation and safety screening to determine whether this treatment is appropriate.
Our team carefully considers your medical history, symptoms, and treatment goals to ensure safe, personalized care. Any decision as to whether to prescribe or administer ketamine will be solely determined in the professional clinical judgment of the licensed practitioner.
Ketamine vs. Other Depression Treatments
Traditional antidepressants and psychotherapy are often effective treatments for depression, but they may take weeks to produce results and do not always work for everyone. IV ketamine therapy offers a different approach. Rather than primarily affecting serotonin or other common neurotransmitters, ketamine targets glutamate pathways that support brain connectivity and mood regulation, potentially leading to faster symptom relief for some individuals.
For patients who have not responded to standard treatments, ketamine may provide another path forward.
Care at Accentus Mental Health is personalized and delivered under close medical supervision to ensure safety and effectiveness. Ketamine therapy may also be used alongside ongoing therapy or medication to support a comprehensive approach to managing depression.
Ketamine Infusion Therapy FOR TREATMENT-RESISTANT DEPRESSION (TRD)
For individuals who have encountered challenges in finding effective relief through conventional treatments, IV ketamine therapy shines as a ray of hope, particularly for those with treatment-resistant depression.
IV Ketamine for Depression
Depression, also known as major depressive disorder, is a mood condition marked by persistent sadness, low energy, and a loss of interest in daily activities. These symptoms can significantly affect emotional well-being, relationships, and overall functioning.
When standard antidepressant medications do not provide sufficient relief, the condition is considered treatment-resistant depression.
IV ketamine therapy may help reduce depressive symptoms more rapidly, with some individuals experiencing improvement within hours or days. This faster response can play an important role in stabilizing symptoms and supporting meaningful recovery.
What Other Conditions Can IV Ketamine Help With?
While ketamine is primarily used to treat depression, research suggests it may also help address other complex mental health and neurological conditions. IV Ketamine may be considered for:
- Anxiety disorders
- Post-traumatic stress disorder (PTSD)
- Bipolar depression
- Obsessive-compulsive disorder (OCD)
- Chronic pain conditions
A comprehensive clinical evaluation is required to determine whether ketamine infusion therapy is appropriate for your individual needs.
What You Can Expect During Treatment
IV ketamine therapy at Accentus Mental Health is delivered in a safe, supportive clinical environment, with careful monitoring throughout each stage of treatment to ensure your comfort and safety.
During treatment, you can expect:
- A comprehensive pre-treatment assessment
- A supervised IV infusion session lasting 40–60 minutes
- Continuous monitoring by medical staff
- Temporary side effects, such as dizziness, dissociation, or nausea
- Post-treatment observation before returning home
Our team is available to answer questions and support you throughout the process.
Insurance coverage for IV ketamine infusion therapy depends on several factors, including the patient’s diagnosis and the specific policies of their insurance provider. Unlike intranasal esketamine (Spravato®), intravenous ketamine is typically used off-label for treatment-resistant depression and certain other mood disorders. Because of this off-label status, many insurance plans do not routinely cover ketamine infusions.
At this time, IV ketamine infusions are not consistently covered by Medicare or Medicaid, and patients are often responsible for out-of-pocket costs. As such, Accentus Mental Health offers ketamine therapy via cash or direct payments and does provide this specific treatment though insurance.
KETAMINE THERAPY FAQ
How quickly does IV ketamine work for depression?
Ketamine infusion therapy is known for its rapid onset compared to traditional antidepressants, which may take weeks to show results. With IV ketamine, some individuals notice symptom improvement within hours or days, though response times can vary from person to person.
How is ketamine infusion therapy performed?
IV ketamine therapy is administered through a small catheter placed in a vein in your arm, similar to receiving IV fluids or medication in a hospital setting. The infusion typically lasts 40–60 minutes in a comfortable, supervised environment. You will remain awake throughout the process, and our clinical team will monitor you closely during and after treatment.
Will I need someone to drive me home after treatment?
Yes. Because ketamine may temporarily affect perception, coordination, or alertness, patients should not drive or operate heavy machinery on the day of treatment. You will need someone to take you home after your session, and you can typically resume normal activities the following day.
What are the side effects of ketamine?
Ketamine infusion therapy is generally well-tolerated when administered under medical supervision. Temporary side effects include dizziness, nausea, or changes in perception. Your provider will review your medical history, discuss potential risks, and answer any questions before treatment to help ensure your safety.
Does insurance cover IV ketamine therapy?
IV ketamine therapy is typically not covered by insurance and is offered as a self-pay service. Our team can provide information about costs and payment options during your consultation. We’re here to help every step of the way.
Do I need a referral or consultation?
Referrals for ketamine infusions are welcome but not required. All patients complete a comprehensive evaluation to determine whether IV ketamine is an appropriate treatment option for their individual needs.
